









🐾 Keep your cat flea-free and carefree—twice the protection, zero compromise!
Advantage XD Large Cat Flea Prevention delivers a single topical dose that protects cats over 9 lbs for 2 full months. Featuring a fast-acting, fragrance-free formula with the naturally derived, award-winning ingredient Spinetoram, it kills fleas within hours and outlasts the flea life cycle. Easy to apply and available over the counter, it’s the smart choice for busy cat parents who want long-lasting, eco-friendly flea control.













| ASIN | B0BCX9NJS1 |
| ASIN | B0BCX9NJS1 |
| Active Ingredients | Spinetoram |
| Age Range Description | 8 weeks and older |
| Allergen Information | Allergen-Free |
| Best Sellers Rank | #2,703 in Pet Supplies ( See Top 100 in Pet Supplies ) #15 in Cat Flea Drops |
| Brand Name | Advantage |
| Customer Reviews | 4.3 4.3 out of 5 stars (4,369) |
| Date First Available | September 17, 2022 |
| Dog Breed Size | Large |
| Global Trade Identification Number | 00727804566425 |
| Item Form | Topical |
| Item Type Name | Topical |
| Item Weight | 0.04 Pounds |
| Item model number | CA4242006AM |
| Manufacturer | Elanco US Inc |
| Manufacturer | Elanco US Inc |
| Manufacturer Part Number | CA4242006AM |
| Manufacturer recommended age | 1 month and up |
| Model Number | CA4242006AM |
| Product Dimensions | 4.75 x 4.25 x 0.88 inches; 0.64 ounces |
| Scent Name | Unscented |
| Target Species | Cat |
| UPC | 727804566425 |
| Unit Count | 1 Count |
| Volume | 2 Milliliters |
C**W
Good
I use this on one of the large neighborhood cats to help with his fleas. It seems to work really well for him. He is always highly insulted when I put it on, but in the end, it really helps his comfort level.
T**T
Great product as always!
I’ve used this on my cats for years, and it never fails!
C**Y
Works but leaves a residue
Applied this to my 3 cats about 4 days ago and it appears to have worked! No signs of live fleas on the short haired ones anymore and no side effects to speak of which is great because I was worried about skin irritation from trying a new product. It was easy enough to apply once I realized you didn't have to take the cap completely off and I'm pleased that you only have to apply it once every two months as I am forgetful. My only complaint is that it has been four days and my long haired cat (pictured) still has funky gunky residue on their fur. I applied it at the base of their skull per the instructions and the goo seems to have settled into their hair and is now collecting dust. This is less worrisome for me as my cats don't groom each other but if you have bonded cats this may be a problem as you don't want them ingesting the product. Cleaning it off of my cats neck will also be an issue because washing a cat is a perilous task.
D**N
easy and it works
The day before the hurricane, we were rescued a mother, and two of her three babies sadly, we could not get the third she stayed hidden under a trailer. No one could seem to catch her, especially without hurting her. We were sick about it because it was quite a storm. Bittersweet we got her two days later, but she only lived two weeks. I don’t know besides being runt might’ve been going on. she took to me right away and the whole time here except to go potty she was sleep on my neck cuddled me. She ate well, but never gained weight because of the storm. There were no vets to get to right away. I don’t know if she had a seizure or what but we lost her anyway, this is about the product. I couldn’t put it on the babies. They were too small, but I put it on and what’s great is. It’s good for two months. That evening she had stopped scratching and running a flea come through. Her did not produce very much I am about to order another pack, it was also safe for her because often on they still nurse I did buy the three pack of the regular as well for the three kittens at the time. The surviving to are little chunky monkeys Free of fleas, I have another pack coming for them also. i’d love to use the one on mama on all of them, but it’s just not affordable right now we inherited a small colony of cats besides our hurricane babies Please everyone if you only have a couple of cats please get them fixed. You don’t realize how fast they pop them out most of the time they are inbred You are lucky if they live two weeks. The majority of the time the mothers will reject them almost immediately. They know the babies have problems so they tend to address the healthier. It’s a bit like triage for people you try to save the healthiest that will survive. look around there are places with low cost fees. We only have one. It’s hard to get appointments, but it’s only $35. You are going to pay a lot more than that and cat food and talk about MEDICAL. If you love animals stop them from breeding kittens are grown by about six weeks of age and become little teenagers, I love them all but for people that want kittens you don’t keep them that long and stop the madness
S**L
Flea treatment recommended
This helped getting rid of fleas on my 4 cats. I got enough product for the four of them and used this treatment along with a dawn dish soap bath and gone!! Def recommend getting this!!!
L**G
Not happy, ruined my kittens fur.
Advantage XD I’m am not happy with. I will not put it on my kitten again. She is 8 months old, 6-7 pounds and it made her fur sticky and hard clumps/mats at application site. I applied it directly to her skin as instructed and of course it has to spread as all the topical products do, but it’s not an oily feel on the fur when it disperses, it’s made her fur very clumpy and sticky. It made mats in her fur at the site. I tried to wet her fur down, wipe it off with a wash cloth and a baby wipe and tried brushing her, but it’s pulling and hurting her to do so. It’s like a thin layer of dried syrup on that spot of her head/neck. When I brushed her, so much fur came out of that area I worried she was going to have an allergic skin reaction like a few of the reviews said, luckily skin irritation hasn’t happened. I really am dissatisfied with the product. I have used Advantage II on my previous cats and never have had this happen. The fur on the application site would get a little oily, but not dry like this. I figured I would try the XD since it’s every other month, but this changed my mind so I will not be using it again. Her silky fur is so gross to the touch right now in that area, I am so sad and disappointed. It may be doing its job with the fleas, I really don’t know cause I wanted to use it as a precaution on her. She is strictly indoor but we have a dog (which takes a flea preventative) that goes outside and could bring one in and we don’t want one to move over to her and infest her. After the 2 months are up and she is due for another treatment, I will be looking for a different product. Thankfully I only bought one dose of this stuff.
A**N
Keep tight
Has worked well, ensure you have it tight around the neck as if it is too loose it isn’t as effective and you will still see fleas. Once tight it cleaned them all out
H**R
Sweet.
So far so good. Put on my cat at 2pm and around 8pm, the fleas on his body that you can see in the video were wriggling to their death. Very gross because now their little bodies are all over the sofa and bedding…but whatever’s clever and helps out the kitty.
Trustpilot
2 weeks ago
3 days ago