--- product_id: 574375162 title: "Same and Silybin for Dogs - 90 Soft Chews - S-Adenosyl-L-Methionine, Liver Supplement - Brain Health, Promotes Cognitive Support, Liver Support (Same & Silybin Soft Chews)" brand: "coco and luna" price: "€ 85.09" currency: EUR in_stock: true reviews_count: 9 category: "Coco And Luna" url: https://www.desertcart.de/products/574375162-same-and-silybin-for-dogs-90-soft-chews-s-adenosyl store_origin: DE region: Germany --- # Powerful antioxidant blend Cognitive clarity boost Advanced liver protection Same and Silybin for Dogs - 90 Soft Chews - S-Adenosyl-L-Methionine, Liver Supplement - Brain Health, Promotes Cognitive Support, Liver Support (Same & Silybin Soft Chews) **Brand:** coco and luna **Price:** € 85.09 **Availability:** βœ… In Stock ## Summary > 🧬 Elevate your dog’s vitality with brain & liver power in every chew! ## Quick Answers - **What is this?** Same and Silybin for Dogs - 90 Soft Chews - S-Adenosyl-L-Methionine, Liver Supplement - Brain Health, Promotes Cognitive Support, Liver Support (Same & Silybin Soft Chews) by coco and luna - **How much does it cost?** € 85.09 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.de](https://www.desertcart.de/products/574375162-same-and-silybin-for-dogs-90-soft-chews-s-adenosyl) ## Best For - coco and luna enthusiasts ## Why This Product - Trusted coco and luna brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - β€’ **Antioxidant Armor:** Combats oxidative stress with a potent blend to protect vital organs. - β€’ **Tail-Wagging Taste:** Chicken-flavored soft chews that even picky eaters eagerly take. - β€’ **Liver Love, Inside Out:** Promotes liver cell regeneration and detoxification to keep your pup thriving. - β€’ **Sharper Minds, Happier Dogs:** Supports memory, focus & brain cell communication for your dog's mental edge. - β€’ **Vet-Approved & Hypoallergenic:** Made in the USA with trusted quality for sensitive pups. ## Overview Same and Silybin Soft Chews deliver a clinically inspired blend of S-Adenosyl-L-Methionine and antioxidants designed to support your dog’s liver health, cognitive function, and overall cellular regeneration. Made in the USA, vet-approved, and hypoallergenic, these chicken-flavored soft chews promote mental clarity, liver detoxification, and long-term vitality for dogs of all ages. ## Description desertcart.com : Same and Silybin for Dogs - 90 Soft Chews - S-Adenosyl-L-Methionine, Liver Supplement - Brain Health, Promotes Cognitive Support, Liver Support (Same & Silybin Soft Chews) : Pet Supplies Review: Immediate results, so far... - Well, I have a research background and therefore also a heavy helping of skepticism but was willing to try something to help our 15-16 year old 40 lb rescue mutt who had been showing signs of canine cognitive dysfunction over the past several weeks, and perhaps even longer without us really noticing. She paces and pants, particularly during "sundowning" hours, and at night she would wake up, pace, pant, whine, and paw frantically at her bed while turning in circles (a "nesting" behavior that she has always had but became much more pronounced and prolonged). She also started having accidents in the house, and she has always been a 100% perfectly housetrained dog. So here are the variables I changed, all in a single day: I started giving her this pill (one pill mid-morning and one pill right before bed), started adding salmon oil to her meals (twice daily), incorporated a very short down-the-block-and-back afternoon/evening walk into her regular daily routine (she has hated walks ever since we adopted her), and made a commitment to letting her out to potty more frequently. She is in very good physical health, no signs of arthritis and has maintained good muscle mass. The very first night she slept like a baby. Insert dose of heavy skepticism here. The second night she slept like a baby. So? I remain skeptical but will update if this changes. From what I can see, this has made a very big difference already. She loves the taste of the pill and takes it readily - and she is a VERY picky dog, food-wise. It has not caused any stomach upset and she has a VERY sensitive stomach. We will see... 3-month update: She's still sleeping like a baby through the night and the panting and pacing has disappeared! We have not changed the dose (she gets 2 pills daily - one in the morning and one at night right before bed). She generally seems more alert and sprightly. She doesn't even bother chewing these anymore (they're actually a bit too hard to chew) but no matter...she takes them with gusto and swallows them whole! So glad we started her on these supplements! Almost-1-year update: Our now 16-17-year-old rescue mutt is still doing well and still taking this supplement. We have since added the milk thistle tablets by the same company (the combo of SAM-e + milk thistle are basically what's in the veterinary medicine Denamarin). Our vet agrees that giving our dog these supplements is a good idea. Interestingly, she also said that SAM-e either works like magic, or doesn't work at all. So, I hope that if you are trying this, you have a dog that falls into the "SAM-e works like magic" camp because this has definitely given back our dog's quality of life, and we are thrilled for her to still be with us. Also as a disclaimer, we did have to start our dog on Galliprant (prescription osteoarthritis medicine) as well, which is not surprising given her age, so that definitely also improves her quality of life. We will keep on trucking with our geriatric pup! Final 2020 update: We lost our wonderful girl at the end of June to potential liver and/or cardiac failure. She was probably between 16.5-17 years old. Interestingly she went downhill very quickly - it was like flipping a light switch - and we took her to the emergency vet and let her keep going down the Rainbow Bridge. I do not have lab value evidence that this product worked (we decided to skip bloodwork given our dog's age and anxiety levels at the vet, and knowing that even if we were to find evidence of liver failure, there would not be much we could do) but instead watched her clinical signs carefully. In her last weeks, she was probably uncomfortable but still enjoyed eating (very much!) and was very mobile and able to potty totally normally and rested easily at night. I am thankful that her decline was so sudden and dramatic - it made it "easier" for us to make a hard decision, and she did not suffer long. I can say with certainty that this supplement improved her quality of life and she took it for a full 12 months. Good girl, doggo. Love you forever. Review: Makes dogs feel better - I have used this for 2 of my dogs, and it has worked well for both of them - one geriatric with normal aging signs, and one young diabetic, given to prevent organ damage. Great product. Use with Milk Thistle (same brand) and this combination is the same as giving Denamarin. Not nearly as expensive, and no prescription needed. ## Features - Advanced liver support Provides comprehensive protection and aids in the regeneration of liver cells, promoting optimal liver function and supporting your dog's natural detoxification processes. - Enhanced cognitive clarity Supports sharp mental function, memory recall, and overall neurological health, helping your dog stay alert and engaged as they age. - Brain function optimization Contributes to healthy neurotransmitter production and brain cell communication, essential for focus, learning, and a balanced mood. - Powerful antioxidant blend Combines potent antioxidants to combat free radicals and reduce oxidative stress, safeguarding cells, especially in the liver and brain, for long-term health. - Supports cellular regeneration Aids in the repair and renewal of cells throughout the body, crucial for maintaining organ integrity and overall systemic well-being. - Holistic wellness boost Offers a synergistic blend of ingredients that work together to support not just specific organs but your dog's overall vitality and zest for life. - Made in the USA - All our products are made in the USA and are veterinarian approved as well as hypoallergenic. ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B0CL7XLVMP | | ASIN | B0CL7XLVMP | | Best Sellers Rank | #7,838 in Pet Supplies ( See Top 100 in Pet Supplies ) #44 in Dog Herbal Supplements | | Brand Name | Coco and Luna | | Customer Reviews | 4.2 4.2 out of 5 stars (2,202) | | Date First Available | October 17, 2023 | | Flavor | Chicken | | Item Form | Soft Chews | | Manufacturer | VITA PET LIFE LLC | | Manufacturer | VITA PET LIFE LLC | | Package Dimensions | 4.45 x 3.62 x 3.62 inches; 11.99 ounces | | Target Species | Dog | | UPC | 850051672585 | | Unit Count | 90 Count | ## Product Details - **Brand:** Coco and Luna - **Flavor:** Chicken - **Item Form:** Soft Chews - **Manufacturer:** VITA PET LIFE LLC - **Specific Uses For Product:** Liver Support ## Images ![Same and Silybin for Dogs - 90 Soft Chews - S-Adenosyl-L-Methionine, Liver Supplement - Brain Health, Promotes Cognitive Support, Liver Support (Same & Silybin Soft Chews) - Image 1](https://m.media-amazon.com/images/I/71CcljSTMvL.jpg) ## Available Options This product comes in different **Size** options. ## Questions & Answers **Q: Can i get a refund or replacement? my dog does not like the taste of these tablets at all. i'd prefer to give him capsules. can the seller exchange?** A: They are great about returning items. However, I don't know their policy if they've been opened. I sprinkle mine on his wet food. **Q: Sam e is light sensitive how is this possible in a bottle? Why are they not in blister packs?** A: Dear Valued Customer, We appreciate your interest in our products and your reaching out to us with your question. We believe that light will increase the temperature in the environment and so recommend that the bottle be stored in a cupboard away from sunlight so it will be cooler and better preserved and out of the reach of children and pets. Thank you for your question. We hope this helps and that you and your pet stay healthy and happy. Sincerely **Q: My dog is taking denamarin 425mg. Does this come in 425mg with sylbin** A: Dear Alina, We appreciate you reaching out to us with your question. Our Veterinarian Formulated product, SAMe + Silybin For Large Dogs has 215 mg of SAMe, 235 mg of Silybin Phosphatidylcholine Complex (SPS), and 70 mg of Silybin A+B in each tablet and dogs over 86 pounds would take two tablets. Β You can find the dosages for all sizes of dogs and to match the size of your dog Β on the back of our labels on the product pages. We hope this helps and that you and your dog stay healthy and happy.Β  Sincerely, ## Customer Reviews ### ⭐⭐⭐⭐⭐ Immediate results, so far... *by N***E on June 21, 2019* Well, I have a research background and therefore also a heavy helping of skepticism but was willing to try something to help our 15-16 year old 40 lb rescue mutt who had been showing signs of canine cognitive dysfunction over the past several weeks, and perhaps even longer without us really noticing. She paces and pants, particularly during "sundowning" hours, and at night she would wake up, pace, pant, whine, and paw frantically at her bed while turning in circles (a "nesting" behavior that she has always had but became much more pronounced and prolonged). She also started having accidents in the house, and she has always been a 100% perfectly housetrained dog. So here are the variables I changed, all in a single day: I started giving her this pill (one pill mid-morning and one pill right before bed), started adding salmon oil to her meals (twice daily), incorporated a very short down-the-block-and-back afternoon/evening walk into her regular daily routine (she has hated walks ever since we adopted her), and made a commitment to letting her out to potty more frequently. She is in very good physical health, no signs of arthritis and has maintained good muscle mass. The very first night she slept like a baby. Insert dose of heavy skepticism here. The second night she slept like a baby. So? I remain skeptical but will update if this changes. From what I can see, this has made a very big difference already. She loves the taste of the pill and takes it readily - and she is a VERY picky dog, food-wise. It has not caused any stomach upset and she has a VERY sensitive stomach. We will see... 3-month update: She's still sleeping like a baby through the night and the panting and pacing has disappeared! We have not changed the dose (she gets 2 pills daily - one in the morning and one at night right before bed). She generally seems more alert and sprightly. She doesn't even bother chewing these anymore (they're actually a bit too hard to chew) but no matter...she takes them with gusto and swallows them whole! So glad we started her on these supplements! Almost-1-year update: Our now 16-17-year-old rescue mutt is still doing well and still taking this supplement. We have since added the milk thistle tablets by the same company (the combo of SAM-e + milk thistle are basically what's in the veterinary medicine Denamarin). Our vet agrees that giving our dog these supplements is a good idea. Interestingly, she also said that SAM-e either works like magic, or doesn't work at all. So, I hope that if you are trying this, you have a dog that falls into the "SAM-e works like magic" camp because this has definitely given back our dog's quality of life, and we are thrilled for her to still be with us. Also as a disclaimer, we did have to start our dog on Galliprant (prescription osteoarthritis medicine) as well, which is not surprising given her age, so that definitely also improves her quality of life. We will keep on trucking with our geriatric pup! Final 2020 update: We lost our wonderful girl at the end of June to potential liver and/or cardiac failure. She was probably between 16.5-17 years old. Interestingly she went downhill very quickly - it was like flipping a light switch - and we took her to the emergency vet and let her keep going down the Rainbow Bridge. I do not have lab value evidence that this product worked (we decided to skip bloodwork given our dog's age and anxiety levels at the vet, and knowing that even if we were to find evidence of liver failure, there would not be much we could do) but instead watched her clinical signs carefully. In her last weeks, she was probably uncomfortable but still enjoyed eating (very much!) and was very mobile and able to potty totally normally and rested easily at night. I am thankful that her decline was so sudden and dramatic - it made it "easier" for us to make a hard decision, and she did not suffer long. I can say with certainty that this supplement improved her quality of life and she took it for a full 12 months. Good girl, doggo. Love you forever. ### ⭐⭐⭐⭐⭐ Makes dogs feel better *by R***T on January 7, 2026* I have used this for 2 of my dogs, and it has worked well for both of them - one geriatric with normal aging signs, and one young diabetic, given to prevent organ damage. Great product. Use with Milk Thistle (same brand) and this combination is the same as giving Denamarin. Not nearly as expensive, and no prescription needed. ### ⭐⭐⭐⭐⭐ Good product *by K***C on January 4, 2026* My dog takes these because she cannot tolerate Denamarin. This works really well as her other medication is hard on the liver. Her blood work shows it is working well to keep her liver function values in normal range. She also seems to like the taste of them. My vet recommended them and so do I. ## Frequently Bought Together - Same and Silybin for Dogs - S-Adenosyl-L-Methionine - 90 Soft Chews - Liver Supplements - Brain Health, Promotes Cognitive and Liver Support - Milk Thistle for Dogs - 120 Chewable Tablets - Silymarin - Liver and Kidney Support with EPA & DHA - Detox - Liver Supplement for Dogs with Choline and L-Arginine - Turmeric for Dogs Anti Inflammatory Pain Relief - 120 Chewable Tablets Hip & Joint Support with Curcumin and BioPerine, Antioxidant, Cardiovascular Health --- ## Why Shop on Desertcart? - πŸ›’ **Trusted by 1.3+ Million Shoppers** β€” Serving international shoppers since 2016 - 🌍 **Shop Globally** β€” Access 737+ million products across 21 categories - πŸ’° **No Hidden Fees** β€” All customs, duties, and taxes included in the price - πŸ”„ **15-Day Free Returns** β€” Hassle-free returns (30 days for PRO members) - πŸ”’ **Secure Payments** β€” Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** β€” Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.de/products/574375162-same-and-silybin-for-dogs-90-soft-chews-s-adenosyl](https://www.desertcart.de/products/574375162-same-and-silybin-for-dogs-90-soft-chews-s-adenosyl) --- *Product available on Desertcart Germany* *Store origin: DE* *Last updated: 2026-04-23*